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TUCSON, Ariz. (BFMG) — DNA taken from a pair of gloves found about two miles from Nancy Guthrie’s home did not produce a match in a national database and does not match genetic material recovered at her property, according to the Pima County Sheriff’s Department.
Investigators said the DNA profile from the gloves was uploaded to the FBI’s Combined DNA Index System, or CODIS, but the search did not trigger a hit. The profile also did not match DNA previously collected from Guthrie’s residence.
Authorities said the DNA from the home is still being analyzed and will undergo additional testing as the investigation continues. Detectives are exploring investigative genetic genealogy and other databases beyond CODIS to look for possible matches.
The heightened interest in Guthrie’s disappearance has driven a surge in calls to the Pima County 911 Communications Center. Between Feb. 1 and Feb. 16, 2026, the center logged 28,586 total calls — including 911, non-emergency and administrative lines — compared with 18,451 calls during the same period last year. Non-emergency lines alone received 20,968 calls this year, up from 7,419 in 2025.
Federal officials said the FBI’s National Threat Operations Center has received more than 18,000 tips related to the case since Feb. 1. Threat intake examiners are working around the clock to answer calls to the 1-800-CALL-FBI tip line and review tips submitted online.
Investigators were back at Guthrie’s residence Tuesday conducting follow-up work, but officials did not release details about what they were doing at the scene.
The FBI is offering a reward of up to $100,000.00 for information leading to the location of Nancy Guthrie and/or the arrest and conviction of anyone involved in her disappearance. If you have any information, please call 1-800-CALL-FBI or visit www.tips.fbi.gov.
We will continue to monitor this developing story and update it as details are available from law enforcement working this investigation.
